MALAT1 and breast carcinoma: We then analyzed the expression of MALAT1 in pre-osteoclasts (including monocytes and macrophages) and mature osteoclasts of the non-osteoporotic individual (Fig. 4a, b), osteoporosis patients (Fig. 4c, d), osteosarcoma patients (Fig. 4e, f), and patients with breast cancer bone metastases (Fig. 4g, h).