NLRC4 and infection: Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat and CARD Domain Containing 4 (NLRC4) encodes the key components of inflammasome that function as pattern recognition receptors, NLRC4 plays a critical role in innate immune responses to a variety of pathogens, infection, tissue damage, and other cellular stress through multiprotein inflammasome complexes [11].