For example, a higher abundance of Faecalibacterium prausnitzii, Ruminococcus bromii, Bifidobacterium ssp., Clostridium colinum, Eubacterium rectale, and lower levels of Streptococcus mitis have have been linked to a better treatment response to anti-TNF therapy in IBD patients [64–66]. This evidence concerns the gene TNF and inflammatory bowel disease.