Furthermore, transwell assay showed that the migration rates of HCT 116 and RKO cells in shNUBP2 group were decreased by 50% and 87%, respectively (P < 0.001 for both) (Fig. 3D), suggesting that NUBP2 deletion potently impaired the migratory capacity of CRC cells. The gene discussed is NUBP2; the disease is colorectal carcinoma.