Analysis of T2DM duration by use of antidiabetic drugs among subcohort members revealed that the median T2DM duration in those who used glucose-lowering drugs was shorter than in those with T2DM without antidiabetic drugs (median 6 versus 7 years, respectively), but duration was longer among those who used insulin or analogues (median 8.5 years, data not shown). The gene discussed is INS; the disease is type 2 diabetes mellitus.