To identify BLBC‐specific hyperactive TFs, Enhancer Linking by Methylation/Expression Relationships (ELMER), an available computational method used to identify master TFs of specific cancer subtypes,[12] was employed to identify the differentially methylated TF‐binding enhancer regions and corresponding TFs by using DNA methylation and RNA sequencing (RNA‐seq) data in the TCGA database (Figure S1A, Supporting Information). The gene discussed is TF; the disease is cancer.