Among various ICD strategies, photothermal therapy has emerged as a promising approach for evoking an immune response by transforming immunological “cold tumors” into “hot tumors”.[7] It has been found that mild photothermal therapy (PTT) increases immunotherapy of PD‐L1 mAbs by increasing the recruitment of tumor‐infiltrating lymphocytes and boosting T‐cell activity against tumors.[7c]. This evidence concerns the gene CD274 and neoplasm.