We performed a systematic literature review using PubMed and Web of Science with search terms including “aspirin,” “NSAID,” “statin” (including specific statin drug names), “metformin,” “ACE inhibitors,” and “ARBs” (including specific anti‐hypertensive drug names) in combination with “cancer.” Searches were limited to human studies published between 2000 and 2023. This evidence concerns the gene ACE and cancer.