SRS score = (0.81×TP53 regulates transcription of DNA repair genes) – (1.14×signaling by NTRKs) – (0.42×regulation of RAS by GAPs) – (1.90×FBXW7) – (0.38×DNA double-strand break repair) + (2.27×FBXW7 mutants and NOTCH1 in cancer). This evidence concerns the gene NOTCH1 and cancer.