The T2DM + CAD patients with ɛ4 allele had higher level in LDL-C (2.70 ± 0.76 mmol/L vs. 2.21 ± 0.84 mmol/L) while had higher level in ApoB (0.87 ± 0.23 g/L vs. 0.76 ± 0.26 g/L) than those with ɛ2 allele (all p < 0.05). This evidence concerns the gene APOB and type 2 diabetes mellitus.