POU6F2 and colorectal carcinoma: More importantly, liquid chromatography–mass spectrometry (LC-MS) revealed that knockdown of POU6F2-AS1 significantly decreased FAs levels in CRC cells, such as palmitic acid (C16:0), stearic acid (C18:0), palmitoleic acid (C16:1), and oleic acid (C18:1) (Fig. 3I).