PDCD1 and lung carcinoma: This is in contrast to the counterparts in Ldlr−/− mice AS plaques,70 lung cancer, or other tumors.71 These results suggest that the deficient expression of PD-1 ligands in human AS plaques might contribute to forming the pro-inflammatory phenotype of PD-1+ T cells and their differentiation routines into the long-lived LMNA+ Tem cells.