Notably, SNV alterations in TP53 were detectable in many malignancies, with 7 out of 22 cancers tested having an AUC of at least 0.7 and 14 of them showing AUCs greater than 0.65, reaching up to 0.841 for brain LGG, up to 0.785 for BRCA and up to 0.771 for endometrial cancer. Here, TP53 is linked to cancer.