Almost all of the top-performing genes were that of over-expression, with PMS2 in THYM; CARD11, LASP1, STIL, POLE, KMT2C, and CLIP1 in testis cancer; ERC1, WRN, OLIG2, FANCC, and ACSL6 in ACC; and SOX2 and NDRG1 in ESCA leading in performance with AUCs ranging 0.832-0.911. Here, SOX2 is linked to testicular cancer.