AFP and hepatocellular carcinoma: In addition, hepatic damage was determined by the serum enzyme activity of GGT and ALT, and for determining the HCC development, AFP levels were measured (Fig. 1C); ALT and GGT activities showed a tendency to increase with no significant differences in the HCC group when compared with the control group; likewise, the HCC/IFC-305 and IFC-305 groups do not show changes compared to the control group.