CNOT3 and leukemia: The interaction of CNOT3 with the translational machinery is well aligned with the results on CNOT3 structure-function (Fig. 3B) and the link between CNOT3 and AU3 vs. GC3 content of mRNAs (Fig. 5C–E), pointing to a dominant role in codon sensing and modulation of translation activity by CNOT3 in leukemia.