Robust evidence was observed for circulating phosphorous (per SD, OR = 1.19, 95% CI: 1.09, 1.31), leukocyte telomere length (LTL) (long versus short, OR = 1.37, 95% CI: 1.25, 1.50), serum uric acid (per SD, OR = 1.12, 95% CI: 1.00, 1.26) increasing risk of prostate cancer, and alanine aminotransferase (per SD, OR = 0.43, 95% CI: 0.27, 0.68), albumin (per SD, OR = 0.79, 95% CI: 0.68, 0.91) reducing risk of prostate cancer. The gene discussed is GPT; the disease is Familial prostate cancer.