TSG101 and viral infectious disease: Moreover, as the PEDV or PEAV M protein is continuously truncated, the interaction region was identified as 156–172aa, which did not contain similar late structural motifs but contains a proline conserved region "PXFV" (S5D–S5H Fig), suggesting that PEDV and PEAV may recruit TSG101 to participate in viral infection through other conserved motifs or in more complex ways, which requires further investigation.