MFN2 and neoplasm: It is not clear if the captured tumor cells take up this mitochondria upon arrival, though another study has shown that colorectal cancer cells treated with NETs increased ATP production, upregulated mitochondrial biogenesis associated genes, and had increased expression of Drp-1 and Mfn2, as well as mitophagy-linked proteins, PINK1 and Parkin [156].