To understand the mechanism of JMJD6 in regulating splicing in neuroblastoma, we performed an unbiased identification of JMJD6-interacting partners by introducing a FLAG-tagged JMJD6 into SK-N-AS and BE2C cells, followed by immunoprecipitation to pull down the JMJD6-associated complex and protein identification with mass spectrometry (Figure 6A). Here, JMJD6 is linked to neuroblastoma.