Loss of GABRQ*‐containing neurons is an indicator of early social–emotional cognitive decline in frontotemporal dementia (Gami‐Patel et al., 2022), IL6R* has been associated with memory domain scores, and Alzheimer's disease pathology (cerebrospinal fluid pTau and Aβ42/40 ratio) (Quillen et al., 2023), and DTNB is an indicator of extent of neuronal injury and inflammation in Alzheimer's disease (Neumann et al., 2022). The gene discussed is IL6R; the disease is early-onset autosomal dominant Alzheimer disease.