(b) Analysis of livers of mice treated with CCl4, a well-established inducer of liver fibrosis (23), showed a significant increase in the number of FUS-positive cells compared with vehicle-treated cells (Figure 7, A and B); FUS-positive cells also stained for desmin (Figure 7A), a marker of hepatic stellate cells (HSCs) (24), which play a key role in the fibrosis process (25). Here, DES is linked to Hepatic fibrosis.