Uemur et al. also found that ARBs can inhibit prostate cancer cell proliferation by suppressing epidermal growth factor (EGF) expression and mitogen-activated protein kinases (MAPK) and signal transducer and activator of transcription 3 (STAT3) phosphorylation pathways induced by angiotensin II [12]. This evidence concerns the gene EGF and prostate carcinoma.