Tianhua Fu et al. investigation proved that α-Mangostin (12.5 and 25 mg/kg) has a hepatoprotective effect on LPS-induced acute liver failure in mice via the reduction in MDA, TNF-α, aspartate transaminase (AST), serum alanine aminotransferase (ALT), interleukin-1β, -6 levels. This evidence concerns the gene GPT and acute liver failure.