CRP and irritable bowel syndrome: Similarly, it has been reported that median high-sensitive CRP levels in the IBS group were significantly higher than in healthy controls (1.80, IQR 0.7–4.04 mg/l vs 1.20, IQR 0.5–2.97 mg/l respectively, p < 0.006,) with the highest levels in IBS-D patients showing greater symptoms severity [80].