The following parameters were univariate associated with in-hospital mortality: need for KRT, AKI stage 3, need for invasive mechanical ventilation, sepsis, need for vasopressors, liver cirrhosis, active malignancy, high APACHE II or SOFA score, MAP, heart rate, myoglobin, urea, creatinine, IL-6, albumin, platelet count, pH, bicarbonate, potassium, lactate level and diuresis at admission. The gene discussed is IL6; the disease is Sepsis.