SNCA and synucleinopathy: Deletion of synuclein is associated with the development of progressive neurological impairments, while its loss of function/gain of toxicity due to e.g. aggregation is implicated in the pathogenesis of synucleinopathies, neurodegenerative disorders that include Parkinson’s disease (PD) and dementia with Lewy bodies (DLB)7,8.