SREBF2 and hepatocellular carcinoma: In our HCC cohort containing 80 pairs of HCC tissues and matched noncancerous liver tissues, MeRIP assays were undertaken to measure m6A modification level of SREBF2-AS1, and the results showed that the m6A modification level of SREBF2-AS1 was increased in HCC tissues compared with noncancerous liver tissues (Fig. 2D).