Considering the crucial role of NAMPT in modulating insulin sensitivity and its consequential impact on ovarian function, targeting and regulating the expression of this gene and its corresponding non-coding RNAs including XIST, hsa-miR-144-3p, and hsa-miR-1271-5p, offer a promising approach to alleviate the pathological symptoms associated with PCOS. Here, NAMPT is linked to polycystic ovary syndrome.