Thedevice can identify the presence of Ag85B spiked in artificial sputum.Moreover, bovine serum albumin (BSA)-blocked Ab85B-SWCNT FET devicescan detect Ag85B spiked in serum and can distinguish TB-positive clinicalsamples from negative samples under 10 min with portable Metrohm potentiostat,highlighting the potential practicality of our biosensor for TB diagnosis.The robustness of the Ab85B-SWCNT devices to biofluids was furtherenhanced by integrating a BSA cross-linking blocking layer onto SWCNTnetworks. This evidence concerns the gene ALB and tuberculosis.