Diabetic kidney disease (DKD) is characterized by impaired renal function and/or elevated urinary albumin excretion.[1] Approximately 40% of patients with diabetes mellitus will develop DKD, even end‐stage renal disease.[2] The key mechanism driving the progression of DKD is podocyte injury, which plays a pivotal role in mediating urinary albumin excretion, glomerulosclerosis, and the decline of renal function.[3] Podocytes are terminally differentiated epithelial cells of the renal capsule, equipped with primary, secondary, and tertiary foot processes. This evidence concerns the gene ALB and diabetic kidney disease.