NCOA3 and cancer: The Nuclear receptor coactivator (NCOA) family which includes NCOA1, NCOA2, and NCOA3, serves as transcriptional coactivators for NRs and other transcription factors.[16] The presence of multiple LXXLL motifs on NCOAs facilitates their physical binding with agonist‐bound NRs, forming NRs boxes.[17] NCOAs have been implicated in various diseases, such as cancer, arthritis, and immune response.