NCOA3 and diabetic kidney disease: To elucidate the role of NCOA3 in podocyte injury and DKD in vivo, the DKD model was established with Cre+/NCOA3fl/fl and Cre−/NCOA3fl/fl mice by high‐fat diet (HFD) followed by unilateral nephrectomy and streptozocin (STZ) injection, as illustrated in Figure 5A.