Intriguingly, the high tumor‐associated neutrophil (TAN) populations in the myeloid cell‐enriched subtype are associated with an unfavorable prognosis.[40] Autologous CD8+ T cells co‐cultured with human TANs (marked increase in CD274) exhibited lower proliferation properties as well as lower levels of cytotoxic granule proteins, whereas other CCL4+ TAN subsets expressed high levels of the chemokine genes CCL3 and CCL4, which could recruit macrophages,[40] demonstrating that they have different functions. This evidence concerns the gene CCL4 and neoplasm.