NPY and posterior cortical atrophy: In addition, one study showed that PCa epithelium‐upregulated NPY could antagonize apoptosis, increase motility, and cause energetic metabolic pathway changes.[32] Here, we found that NPY was upregulated in low‐grade cancer cells and normal‐like epithelial subpopulations, indicating that NPY may serve as a driver or indicator of PCa initiation.