Oral administration of EPS obtained from Lactobacillus acidophilus on rats that developed 1,2-dimethyl hydrazine–induced colon cancer decreased the number of polyps, restored the levels of antioxidative enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and vitamin C to near normal levels, which decreased in the colon during carcinogenesis [125]. This evidence concerns the gene CAT and colonic neoplasm.