The experiment found that compared with other dialysis patients, peritoneal dialysis patients with a history of peritonitis had significantly lower levels of SIRT6 and E-cadherin in peritoneal mesothelial cells compared to patients without a history of peritonitis, while levels of vimentin and TGF-β1 were higher than those without a history of peritonitis. The gene discussed is VIM; the disease is peritonitis.