TGFB1 and Peritoneal Fibrosis: At present, it has been found that the mechanisms leading to peritoneal fibrosis include MMT in peritoneal mesothelial cells, increased extracellular matrix production, angiogenesis, and transforming growth factors β1 (TGF-β1) Overexpression, induction of renin angiotensin activation, and increased expression of fibronectin (FN) [11–13].