BMP4 and lung cancer: Furthermore, miR-196b has been found to promote the migration and invasion of lung cancer cells by targeting GATA6 levels (Liang et al. 2020; Li et al. 2018), while miR-200 downregulates bone morphogenetic protein-4 (BMP4) expression by directly reducing GATA6 gene transcription, thereby impeding lung cancer cell growth and metastasis (Yu et al. 2022).