We confirmed the presence of Aβ signatures including Aβ40 (86.3 ng mL−1), Aβ42 (12.6 pg mL−1) (Figure 1d),[16] and Aβ plaques (Figure 1k and Figure S2a, Supporting Information).[12, 17] In response to amyloid deposition, glial activity was increased in AD conditions; including activated astrocytes and microglia as detected by increased glial fibrillary acidic protein (GFAP)[4, 18] and cluster of differentiation 86 (CD86) expression,[19] respectively (Figure 1c,l,m and Figure S2a,b, Supporting Information). This evidence concerns the gene CD86 and Alzheimer disease.