LACTB and infection: In the past 2 decades, the acquired MDR infections have increased because of the production of beta-lactamase enzymes (including extended-spectrum β-lactamases (ESBLs), carbapenemases, and metallo-β-lactamases), which leads to 3rd-generation cephalosporin and carbapenem resistance (Aslam et al., 2018; Vestergaard et al., 2019).