PLP2 and neoplasm: The C0 TMPRSS2+ Tumor EPCs subgroup was mainly displayed at the beginning of the trajectory and in the branch with the first branch point down (corresponding to state1 and state2), the C1 ANKRD36C+ Tumor EPCs subgroup was mainly in the branch with the second branch point up (corresponding to state4), and the C3 PLP2+ Tumor EPCs subgroup mainly existed at the end of the whole pseudotime sequence trajectory (corresponding to state5).