The results of GSVA suggested that ARDEGs were enriched in some important pathways, most of which were also liver immune microenvironment pathways, including KEGG endocytosis, KEGG lysosome, KEGG antigen processing and presentation, KEGG extracellular matrix receptor interaction, KEGG autoimmune thyroid disease, and KEGG P53 signaling pathway (Supplementary Figure S3A, Supplementary Table S6). The gene discussed is TP53; the disease is autoimmune thyroid disease.