RB1CC1 and Hepatic fibrosis: These results suggest that macrophage, Th17 cell, natural killer cell and CD56dim natural killer cell are down-expressed in the progression of hepatic fibrosis; Combined with the negative correlation between RB1CC1 and the above four kinds of immune cells, RB1CC1 may promote the progression of liver fibrosis by regulating macrophage, Th17 cell, natural killer cell and CD56dim natural killer cell.