Recurred glioma = 7/836/42 had detectable CTC.CTCs higher in astrocytomas compared to oligodendrogliomas.Large number of CTC-WBC clusters detected and could help monitor. Recurrence. No difference noted in glioma subtype.CTC level related to P53 mutation, IDH1 status and poor outcome. Resection may promote CTCs in gliomas. This evidence concerns the gene TP53 and astrocytoma (excluding glioblastoma).