Similarly, knockdown or overexpression of SLC2A1-DT reduced or induced the protein expression but not mRNA expression of β-catenin in HCC cells (Fig. 4A and B, Fig. S3C and D), which was remarkably rescued or reversed by ectopic expression and depletion of YWHAZ (Fig. 4C-D, Fig. S3E-H). Here, SLC2A1 is linked to hepatocellular carcinoma.