The top-regulatedgenes included METTL7A, ALPL, SUSD2, IGFBP5, CORO1A, CXCL8, LCN2, NRP1, and CTNNA2, which are involved in tumor proliferation, angiogenesis,migration, metastasis, and tumor immunity. This evidence concerns the gene CXCL8 and neoplasm.