The high expression of the lncRNA HAGLR complementary chain (HAGLROS) is associated with the shortened survival time of patients with CRC; HAGLROS induces CRC cell apoptosis and suppresses autophagy through the miR-100/ATG5 and PI3K/AKT/mTOR pathways (Zheng et al., 2019). Here, AKT1 is linked to colorectal carcinoma.