The BDNF-AS/WD repeat domain 5 (WDR5)/F-box and WD repeat domain-containing 7 (FBXW7) axis regulates ferroptosis in gastric cancer cells by affecting the ubiquitination of voltage-dependent anion channel 3 (VDAC3) (Huang G. et al., 2022). The gene discussed is WDR5; the disease is gastric cancer.