Extracellular matrix (ECM) remodeling is another important component in the pathophysiology of BPD, and RNA sequencing of fetal lungs at 24 h after LPS exposure showed significant modulation of genes related to ECM remodeling (Cxcl1) and organization, collagen synthesis (Col9a2, Col9a1, Col11a2, Col11a1), proliferative mesenchymal progenitors and matrix fibroblasts. The gene discussed is COL11A1; the disease is bronchopulmonary dysplasia.