VPS35 and Global developmental delay: Interestingly, the NAA60-SLC20A2 network from the caudate tissue is already linked to genes implicated in Mendelian disorders associated with clinical overlap with the NAA60-related phenotype, such as developmental delay, intellectual disability, variable dysmorphic facial features (NARS,OMIM:108410; USP7,OMIM:616863; CSNK2A1, OMIM:617062), and parkinsonism (VPS35) (Fig. 6g and Supplementary Fig. 5g).