These experiments complemented the results obtained in the bioinformatic analyses and unraveled that ANKRD6 confers pro-metastatic and tumorigenic properties to GC cells, preventing apoptosis, promoting GC cell migration and invasion, fostering tumor growth, and regulating EMT related pathways but also hallmarks such as G2M checkpoint or KRAS signaling. The gene discussed is ANKRD6; the disease is neoplasm.