In this experiment, the MTT assay was performed after simultaneously treating B16F10 melanoma cells with α-MSH (200 nM) and THWE and THEE (25, 50, and 100 μg/ml) to examine the effect of the T. himalayense NIBR0000505337 extracts on B16F10 melanoma cell survival. This evidence concerns the gene STAMBP and melanoma.