Also, Kuang et al. (2017) discovered that upregulation of BST2 results in platinum resistance in patients with locally advanced NPC by activating the NF-κB pathway, which regulates tumorigenicity, proliferation, chemoresistance, and radioresistance of multiple kinds of cancers, including NPC (Zhan and Fan, 2020). Here, NFKB1 is linked to cancer.