We chose to focus on STAG2 because of its importance as a tumor-suppressor gene lost in various cancers, PAXIP1 a recently identified cohesin regulator, and the Haspin kinase since it may be targetable with small molecules (Liang et al. 2018; Bailey et al. 2021; Mayayo-Peralta et al. 2023). Here, STAG2 is linked to cancer.