Thirty-seven HRRGs had effects on the prognosis of BC patients, with some HRRGs having a significant positive correlation with prognoses, such as SLX4, RAD54L, RECQL4, and RECQ, and some HRRGs, including RAD51B, RAD50, and PD55B, were negatively correlated with prognosis (Fig. 2A). The gene discussed is RECQL4; the disease is breast cancer.