CD4 and Alzheimer disease: The result also displayed a high relative abundance of 12 immune cell populations in cluster B, including naive and resting memory CD4 T cells, regulatory T cells, follicular helper T cells, naive and memory B cells, M1 Macrophages, resting and activated Mast, Monocytes, neutrophils, and endothelial cells, suggesting that these cells may be involved in the necroptosis mechanism of AD.